A PhD Fellowship in B-cell development in Porse Group at Finsen Laboratory & BRIC, University of Copenhagen
The group and our research
Research in the Porse group is focused on elucidating mechanisms governing normal and malignant hematopoiesis with special emphasis on the behaviour of hematopoietic stem cells (HSCs) during adult hematopoiesis and leukemic stem cells (LSCs) in acute myeloid leukemia. To this end, we employ mouse models of human AML, mouse knock-out lines of putative HSC/LSC regulators, primary patient material and a broad range of bioinformatics tools. We have also conducted a number of shRNA-based in vivo screens for genes involved in tumor maintenance and identified a number of novel potential oncogenes and tumor suppressors which will be studied in future projects.
The Porse group is affiliated with the Finsen Laboratory (www.finsenlab.dk) at Rigshospitalet as well as BRIC (www.bric.ku.dk) and DanStem (www.danstem.ku.dk), both University of Copenhagen.
Project/ The research project(s)
The project deals with the characterization of the role of a newly identified transcription factor in B-cell development. Specifically it involves the characterization of a conditional mouse knockout using flow cytometry, ChIP-seq, ATAC-seq, RNA-seq as well as functional assays.
Start: Preferably 1 March 2016 or after agreement.
Qualifications
We are looking for a highly motivated and enthusiastic candidate with the following qualifications:
- A Master of Science in life science
- Documented experience in flow cytometry
- Knowledge about hematopoietic development as well as transcriptional and epigenetic control of gene expression
- Hands-on experience in deep-sequencing based technologies
- Excellent communication skills in English
To be considered for the position as PhD fellow, it is a condition, that your Master of Science degree is considered to be equivalent to a Danish Master of Science (http://fivu.dk/en).
For further information regarding the position, please contact Prof Bo Porse (bo.porse@finsenlab.dk)
Place of employment and work
The employment and place of work is at BRIC, University of Copenhagen. BRIC is located close to the centre of Copenhagen, in the Copenhagen Biocenter. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories, a number of cutting-edge core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory and a well-functioning administrative and technical support. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://www.eu-lide.eu/.
Terms of salary and employment The appointment as PhD fellow is for 3 years. It is conditioned upon the candidates’ successful enrolment in the PhD programme. Salary, pension and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 25.556 DKK (ca. 3.450 EUR) plus pension.
Application Your application must be submitted electronically by clicking ‘Apply now’ below or via BRIC’s website on http://www.bric.ku.dk/jobs/. The application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page)
- Curriculum vitae incl. education, experience, language skills and other skills relevant for the position
- A certified/signed copy of Master of Science certificate. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do
- Publication list (if possible)
Letters of recommendation Furthermore, the applicant should provide two letters of recommendation. To be taken into consideration, the letter must be signed by the supporting person on paper with institutional letter head and in PDF-format. They should be sent before deadline to jobvacancy@bric.ku.dk with subject “candidate’s last name Porse_PhD_Dec15”; preferably by the supporting person. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.
Application deadline: December 27, 2015
We reserve the right not to consider material received after the deadline, and not to consider applications or letters of recommendation that do not live up to the above-mentioned requirements.
We reserve the right not to consider applications or supplementary material received after deadline, and not to consider applications or letters of recommendation that do not live up to the above-mentioned requirements.
The further process
Shortlist: After expiry of the application deadline, the superior with power to appoint selects a number of applicants for assessment on the advice of the Appointments Committee. All applicants are immediately notified whether their application has been passed for assessment. Applicants who were not passed for assessment should not expect further with regard to their application unless the shortlist is revised.
Assessment: The selected applications will be assessed according to the Ministry Order on the Appointment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement.
You can read about the recruitment process at http://employment.ku.dk/faculty/
BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
