Postdoc in Quantitative phosphoproteome analysis of Escherichia coli

Danmarks Tekniske Universitet

Hørsholm, 1 stilling

We are seeking a highly motivated and independent postdoctoral fellow to join an ongoing project at the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain), to work on quantitative analysis of Escherichia coli phosphoproteome. The aim of the project is the reconstruction of the kinase-based regulatory network underlying metabolic adaptation.



Responsibilities and tasks

Successful candidate will join an interdisciplinary team, which currently combines the expertise in proteomics, protein phosphorylation, bacterial physiology and mathematical modelling of biological systems. The candidate will be required to independently carry out quantitative proteome and phosphoproteome measurements on Q-Exactive and Fusion instruments available at the DTU proteomics platform, and perform the associated data analyses. Further, the candidate will be expected to interface with molecular biologists regarding sample preparation, and with the modelling experts regarding data interpretation and integration.



Qualifications

Candidates should have a PhD degree or equivalent.



The candidate should:

•have documented extensive experience (publications) with current methods of mass spectrometry-based proteomics

•be fluent in written and spoken English, and capable of writing research papers independently

•be capable of working in an interdisciplinary working environment



Experience in phospho-proteomics and working with bacteria would be considered as a bonus, but it is not an absolute prerequisite. Preference will be given to candidates with a strong publication record.



We offer

We offer an interesting and challenging job in an international environment focusing on education, research, public-sector consultancy and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world.



Salary and terms of employment

The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.



The period of employment is one year, with possibility of extension.



The place of work will be the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) at Kogle Allé 6, Hørsholm, Denmark.



Further information

Further information may be obtained from Professor Ivan Mijakovic, ivmi@biosustain.dtu.dk.



Candidates are most welcome to seek clarification/consult before submitting their applications.



Application procedure:

Please submit your online application no later than December 31 2015. Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

•Application (cover letter) including at least two reference contacts

•CV

•Diploma (an official translation into English)

•List of publications



Applications and enclosures received after the deadline will not be considered.



All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.



The Novo Nordisk Foundation Center for Biosustainability is an international research center at the Technical University of Denmark funded by a grant of 1.1 billion DKK from the Novo Nordisk Foundation. The Center conducts research in metabolic engineering of cell factories, in silico systems biology and bioinformatics with the purpose of developing new processes and technologies that can support a more sustainable bio-based production of valuable chemicals in the future. The Center brings together some of the world's leading researchers in the field and possesses the advanced equipment and facilities required for achieving its ambitious research goals. Impact on society by innovation has a high priority and the Center collaborates worldwide with biotech companies and chemical industries to facilitate the dissemination and exploitation of its results. Additional information can be found at <a href='javascript:openLinkWindow("http://www.biosustain.dtu.dk")' "="" data-cke-saved-href='javascript:openLinkWindow("http://www.biosustain.dtu.dk")'>http://www.biosustain.dtu.dk.



DTU is a technical university providing internationally leading research, education, innovation and public service. Our staff of 5,800 advance science and technology to create innovative solutions that meet the demands of society; and our 10,300 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.